(CNN) - Barcelona took a big step towards setting up a semi-final showdown with his Spanish rivals Real Madrid beat Shakhtar Donetsk 5-1 to League Champions on Wednesday.
Champions Ukraine are finishes undefeated at home in over two years in advance of the next week return match, but the 2009 titleholders took control of the quarter-final with a general view dominant in the capital of Catalan to match the demolition of four goals of the real of Tottenham on Tuesday.
Andrés Iniesta, playing settled more until his usual midfield role, no signs of nerves for fans of home within two minutes when he arose to the score after Lionel Messi intended pass from strike partner David Villa has been deflected along the way the 2010 World Cup match-winner.
The star of the Spain and then installed Daniel Alves for the second goal in the 34th minute with a pass clever on the defence that the Brazilian fullback pushed wide of goalkeeper Andrei Pyatov and deflected into the net off his right foot.
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Alves turned provider eight minutes after half-time with a low corner that led to the position of central defender Gerard Pique to trigger a deflected shot after folding to lose his marker.
It was Spades the second goal in as many matches, having stolen the winner of the deviated on corner ' Alves against Villarreal Saturday put Barca eight points clear of the real in the La Liga title race.
Shakhtar reduced the deficit to the hands minute when Defender Yaroslav Rakitskiy flew to the station near put freekick Darijo Srna goalkeeper Victor Valdes with her knee.
But the team of Pep Guardiola replied within 60 seconds as striker Messi surged into the penalty box and teed up Seydou Keita, who has crushed a superb left-foot shot into the top corner of the net.
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Attacking Brazilian Luiz Adriano is almost 4-2 with nine minutes to play, but his shot from a tight angle struck the post and bounced safely in the arms of a relieved Valdes.
Messi has the ball in the net soon after, but his supplier Pedro - who made his return from injury as a replacement of the 70 minute for Villa - was found offside.
However, the fifth goal was soon then Alves made his way in the box and provided a perfect crossed for midfielder Xavi - another player to return from injury - to fly in unmarked and sidefoot into the net.